ISLAMABAD: US researchers have planned an entirely new approach to vaccines by creating immunity against the dengue virus without vaccination.
The study demonstrated that animals injected with synthetic DNA engineered to encode a specific neutralising antibody against the dengue virus were capable of producing the exact antibodies necessary to protect against the disease, without the need for standard antigen-based vaccination.
University of Pennsylvania Perelman School of Medicine professor David Weiner said, “We can produce a synthetic immune response by encoding an antibody and delivering it as a non-live, non-viral, non-permanent antibody.”
